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65 For instance, both cancer and neurodegenerative diseases often involve increased oxidative damage, where impaired GST function may exacerbate disease progression

10.4088/JCP.21r14328 16 ArnoldF

To address these gaps, future research should prioritize larger scale multicenter randomized controlled trials with standardized protocols, adequately powered biomarker-guided RCTs with harmonised clinical endpoints plus GSH/GSSG, MDA/TBARS, SOD/CAT/GPx panels, head-to-head monotherapy vs

This may be because of the slow motility (constipation) causing the gas to become trapped in the GI tract for longer compared to the more diarrhea-dominant form of SIBO

And, finally, while glutathione is safe for many people, the effectiveness of glutathione therapy can vary based on your individual health, delivery method, and dosage