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Reduced Joint Deterioration: Histological analysis in animal studies showed that AOD-9604-treated joints had lower degeneration scores compared to untreated controls

ROS enhance tumor survival via NF-B/Nrf2 activation, upregulating antioxidant (SOD) and anti-apoptotic (Bcl-2) mediators, directly driving chemoresistance

Batch cell analysis was then performed using the Gen5 software on the Cytation 5 microplate reader

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Together, these two mechanisms explain why low-dose atropine can paradoxically enhance vagal effects and slow sinoatrial node firing before higher doses shift the balance toward the expected anticholinergic tachycardia