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Sigma, #A8674) and rotenone (5 M

For rd1 , the calibration set consists of the [GSH] and [GSSG] measurements at PN11, PN12 and PN13, and the validation set contains the data at PN15, PN17 and PN28

Thus, glutamine metabolism is intriguingly linked with intricate cell metabolic processes via enzymes associated with mitochondrial glutaminolysis, cytosolic glutamine metabolism, and glutamine-derived metabolites that perform diverse cellular functions

Glutathione itself is a naturally occurring antioxidant found in human cells, but its levels can fluctuate due to lifestyle, environmental exposure, stress, and nutritional habits

Furthermore, the inhibitory effect of ASA on alcohol relapse intake was significantly reduced by the administration of WRW4, an antagonist of the lipoxin receptor FPR2/ALX, suggesting that the generation of lipoxin is the main mechanism behind the reduction of chronic alcohol intake induced by ASA