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Circulating levels of IGF-1, IGF-1R, AGEs, RAGE, and sRAGE in the serum of the patients were measured using Enzyme-Linked Immunosorbnent Assay (ELISA) kits, and other clinical parameters were also measured during hospitalization
Another notable limitation is the potential risk of bias in the included studies

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Toi M, Inada K, Hoshina S, Suzuki H, Kondo S, et al

HCV replication intermediates, in particular dsRNA, are generally sensed by RLRs 40,41,42,43 , despite the recently discovered FAD-capping of the viral genomes 44
