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In rodent models, blocking NNMT with 5-Amino-1MQ led to lower fat mass, more energy burn, and better insulin response all without cutting calories
These findings suggest that both NNMT and its product MNA increase Sirt1 protein expression, while Sirt1 is needed for the regulatory effects of NNMT and MNA on glucose metabolism [14]
The math below uses a 10 mg vial because that is the most common size for research-grade MOTS-c
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