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In one program, a separate NNMT inhibitor reduced 1-methylnicotinamide levels and improved insulin sensitivity and glucose tolerance in DIO mice, with these effects absent in NNMT-knockout animals

10.1186/s40101-018-0164-z 230 OBrien JT.FirbankM

Low-dose aspirin does not appear to have this effect (Renaud, Nutrients 2024)

Antioxidant enzyme activities and malondialdehyde levels in patients with obsessive-compulsive disorder
