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What makes AOD 9604 interesting is its selectivity

Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant app/Ps-1 Knock-in mice: toward therapeutic modulation of mild cognitive impairment

Biomolecules 10 , 447 (2020)

Electrochemical studies revealed that transition metal substitution significantly influenced the catalytic performance

Overexpression of ALAS2 or supplementation of glycine (an ALA precursor), could not rescue heme synthesis in ABCB10-deficient cardiomyocytes, leading to their conclusion the only reason for the heme defect was that ABCB10 promotes export of ALA from the mitochondria