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elegans LDs revealed that the short-chain dehydrogenase DHS-3 that belongs to the HSD family was almost completely localized and highly enriched on the surface of the LDs [216]

this approach may increase the likelihood of identifying potential index FH cases

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On the contrary, in the distal part of flap skin perfusion further decreased and remained very low even on days 6 and 8 leading to necrosis (Fig 1B and 1C)