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This theory is that free radicals, as by-products of mitochondrial oxidative metabolism, cause cumulative cellular damage that results in overall loss of organismal fitness over time

J Pineal Res 40:195203

There was also no significant difference found in the general distribution of specific hangover symptoms

Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, et al

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