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The acquired resistance of tumor cells to TKIs is partially reversed by inhibiting IGFBP-1 and the combination of antiangiogenic TKIs and IGFBP-1 inhibitors may be a promising therapeutic strategy for HCC (135)

Increasing intracellular glutathione shows promise in controlling symptoms and progression of tissue destruction associated with autoimmunity

ElNashar, N

Since RCD pathways are fundamental to the genesis of all tumors, they present clear targets for therapeutic intervention in all cancer types (Koren and Fuchs, 2021
