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(c) the NADP + -independent hydrolysis of 10-FTHF to formate and THF [34]

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A recent systematic review and meta-analysis highlighted the high global prevalence of diabetic foot ulceration among DPN patients, emphasizing the critical need for early detection and comprehensive management strategies to prevent severe outcomes

doi: 10.1016/j.devcel.2020.12.010 19 LanLXuDYeGXiaCWangSLiYet al