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Renal tubulointerstitial hypoxia: cause and consequence of kidney dysfunction

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In recreational athletes, supraphysiological GH doses are often used either alone or in combination with other doping substances (140), and studies have shown that GH improves anaerobic sprint capacity, but not strength and endurance (141), and increases GH, IGF-I and fasting insulin levels (142, 143) mimicking those seen in acromegaly patients ( Table 1 )

According to a 2019 review in Acta Haematologica, up to 70% of patients on oral iron report gastrointestinal side effects (nausea, cramping, constipation), while IV iron bypasses the gut entirely

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