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an isolated nucleic acid molecule encodes an antibody that specifically binds to an EphA2 polypeptide, said antibody comprising a VH domain having the amino acid sequence of the VH domain of 1C1

This means the aging brain presents not only a decreased ability to control oxidative stress but, as important, it has a decreased capability to regulate ROS mediated signalling, which is associated to the loss of cognitive function [158]

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