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First, WM is intrinsically more vulnerable to hypoperfusion because the major blood supply for WM is via long arterioles that arise from the border zone between the middle cerebral artery and the anterior cerebral artery (Moody et al., 1990)

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Murray AJ, Rogers JC, Katshu MZUH et al (2021) Oxidative stress and the pathophysiology and symptom profile of Schizophrenia spectrum disorders

Overexpression of Human Thioredoxin in Transgenic Mice Controls Oxidative Stress and Life Span

What causes this decline
