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Because of the influences of age, gender, and unhealthy lifestyle factors such as tobacco smoking, alcohol abuse, inadequate dietary habits, and lack of physical activity, there is no consensus on what levels constitute hyperhomocysteinemia at the present time

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These epigenetic shifts can deregulate tumor-related genes, setting the stage for malignant transformation [79]
Molecular modeling further suggested that glyoxalase 1 ( GLO1 ), monoamine oxidase B ( MAOB ), melatonin receptor 1A ( MTNR1A ), and solute carrier family 6 member 4 ( SLC6A4 ) are potential targets of luteolin, which may further shed light on the antidepressant effects of ZZHPD
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