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10.1016/j.redox.2022.102570 64 LiuS.SunC.TangH.PengC.PengF

del Olmo, J

None of the patients recruited in the final cohort were prescribed either cyanide, carbamazepine, valproic acid or iron, which can cause secondary hyperammonemia as a result of disruption of mitochondrial pathways (17,18)

Related to epigenetic considerations, the level of mtDNA mutations positively correlates with BACE1 activity in aging, DS, and DSAD specimens, whereas mtDNA copy number is inversely correlated with insoluble A40 and A42 levels (437)

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