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(1) [Initial Clinical Trial] Helped improve pigmentation darkened by indoor factors (blue light) with a 5.268% improvement rate after 2 weeks of use

& Weitzman, J

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Via ketopinic acid functionalized 2(3 H )-oxazolones When oxazolone 36 derived from ( R )-()-ketopinic acid was reacted with bromine and trimethyl orthoacetate the enantiomerically pure bromomethoxy derivative (4 R ,5 R )- 37 was prepared after crystallization of the reaction mixture
The numerical values for tolerability and safety variables were summarized descriptively for the safety population
