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doi: 10.1093/gastro/goz004
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Studies have shown that hesperidin can reduce reactive oxygen species (ROS) levels by 60% and increase the activity of antioxidant enzymes like glutathione peroxidase (GPx) in cancer cells, leading to decreased oxidative damage and cell growth
Emerging evidence indicates that immunosuppression facilitates fungal translocation into internal organs, thereby potentiating tumorigenesis and malignant progression (Spatz and Richard, 2020)
Then, glutamate can be converted to -KG by GDH
