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Similarly, fatty acid oxidation (FAO), the main pathway of fatty acid catabolism, promotes the activation of NLRP3 through NADPH oxidase 4 (NOX4)

Spherocytosis is distinctive but not pathognomonic, as spherocytes are also seen in other disorders associated with red cell membrane loss, such as in autoimmune hemolytic anemia

Another therapeutic plant extract that seems to have a beneficial effect on NAFLD-related oxidative stress is the blue honeysuckle (BH), common name for Lonicera caerulea

Regulation: The activity of methionine synthase is regulated by various factors, including the availability of methylcobalamin (vitamin B12) and folate derivatives