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Surgery for Obesity and Related Diseases 14: 277283, 2018

In terms of immunometabolic regulation, multiple studies in tumor and inflammatory models have shown that the PI3K/Akt/mTOR pathway can support macrophage polarization toward an M2-like phenotype by promoting metabolic reprogramming processes such as oxidative phosphorylation and fatty acid oxidation (107, 109)

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Researchers have utilized TSPBA to react with PVA, resulting in an injectable hydrogel designed for delivering bFGF, which can be released upon exposure to elevated concentrations of ROS surrounding ischemiareperfusion myocardium [337]

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