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Therefore, the increased activities of ADH and ALDH promote ethanol metabolism and help rapidly eliminate toxic metabolites
Despite promising preclinical data, challenges such as poor bioavailability, dose-dependent safety concerns, and the need for large-scale randomized clinical trials and regulatory standardization remain
In the AIM-HIGH trial, 4 cases (0.2%) of rhabdomyolysis were reported in the niacin
Cell Host Microbe 5 , 593601 (2009)
Chi Z, Chen S, Xu T, Zhen W, Yu W, Jiang D, Guo X, Wang Z, Zhang K, Li M, et al
