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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Cusi K., Isaacs S., Barb D., Basu R., Caprio S., Garvey W.T., Kashyap S., Mechanick J.I., Mouzaki M., Nadolsky K., et al
An open trial that included 32 women with PCOS found a multi-nutrient supplement providing 400 mcg (680 mcg DFE) 5-MTHF daily for three months decreased homocysteine levels compared with no treatment
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Susceptibility to Oxidative Damage:Neuronal mitochondria are rich in polyunsaturated fatty acids (PUFAs), which are prone to lipid peroxidation by ROS, leading to membrane dysfunction and cellular damage
Cell 171 , 696709 (2017)
