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Another very important complication is PAD which is an atherosclerotic occlusive disease of the lower extremities

most commonly used concentration for surgical and obstetric applications 0.75% Bupivacaine: Epidural anesthesia for major surgery

2000;53(6):274278) Authors : F

doi: 10.1038/nm.3882

The trade-off is that higher doses later in your protocol will require drawing larger volumes, potentially exceeding the 100-unit syringe capacity at doses above 1mg to 2.5mg depending on concentration
