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Although amelioration of penile deformity was not examined in an RCT comparing shock wave therapy alone with shock wave therapy plus PDE5Is, other investigators drew the conclusion that continuous therapy of PDE5Is may be a candidate in treatment of PD based on the significant improvement of observational parameters (Palmieri et al., 2012

Adv Pediatr 42:209242 Badve MS, Bhuta S, McGill J (2015) Rare presentation of a treatable disorder: glutaric aciduria type 1

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Accordingly, luteolin-mediated activity could potentiate the sensitivity of CRC cells to chemotherapeutic agents such as oxaliplatin, as OCTN2 is a determinant factor in oxaliplatin uptake [60]