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Clinical aspects of growth hormone deficiency in adults

Typical Clinical Ranges Loading Phase: 25 mg per week (subcutaneous injection) for 46 weeks Maintenance Phase: 2 mg every 12 weeks after the loading period Key Considerations Personalization: Dosage should be adjusted based on individual symptoms, sensitivities, and treatment response

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Over time, these polyps evolve into highly dysplastic advanced adenomas, leading to the loss of epithelial structure and function, and ultimately progressing to invasive carcinomas (Li et al., 2024