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HNE treatment alone (3 M) had no effect on cell death, but HNE significantly decreased the magnitude of LPS-nigericin stimulated cell death as indicated by membrane blebbing, LDH release, and nucleic acid staining in mouse and human macrophages (Fig

The protective effects of J2-5 and J2-9 against oxidative stress were explored, J2-9 demonstrates a superior antioxidant ability in this test, the SOD enzyme activity of each group are as follows, NegCon: 94.02 5.84 (U/mL), Con: 30.72 3.36 (U/mL), J2-5 + 293T: 39.25 3.61 (U/mL), J2-9 + 293T: 50.81 1.05 (U/mL)

27 , 977987.e4 (2018)

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In 2010, he and science writer Adam Marcus launched Retraction Watch