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Mitochondrial autophagy (mitophagy) ensures the selective degradation of damaged mitochondria, maintaining quality control

In addition, as for DRG cells, NF-E2-related factor 2 (Nrf2) that upregulates the expression of antioxidant enzymes (e.g., SOD, CAT, and glutathione-S-transferase (GST)) to eliminate oxidative stress, would be disrupted by accumulated Pt drugs ( Regarding ion channels, TRP play a key role in aggravating cold abnormal pain, among which, TRPA1 and transient receptor potential melastatin 8 (TRPM8), as cold-sensitive receptors, could be activated by ROS (Shimizu et al., 2014

Participants receiving different forms of glutathione in studies have experienced varying outcomes

Evaluation of Detergents for the Soluble Expression of Alpha-Helical and Beta-Barrel-Type Integral Membrane Proteins by a Preparative Scale Individual Cell-Free Expression System

10.1016/s0165-1781(03)00124-0 103.Savitz J , Hodgkinson CA , Martin-Soelch C , et al