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doi:10.1007/s11695-018-3557-5 Fantus RJ, Halpern JA, Chang C, et al

Beyond its metabolic role, NAD+ also participates in DNA repair and cell signaling, making it essential for maintaining cellular health and viability

The -SH groups require re-oxidation to the disulfide (S-S) form to regenerate lipoate as a competent acetyl acceptor

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