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Therapeutic approaches that target chronic hypoxia in CKD HIF stabilizers Oxygen-dependent prolyl-hydroxylases (PHDs) are key regulators of HIF-dependent erythropoiesis, providing an essential theoretical basis for applying HIF-PHD inhibitors (HIF-PHIs) to treat renal anaemia

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The Role of Vitamin B12 Numerous biological processes, including the synthesis of red blood cells, the synthesis of DNA, and the normal functioning of the nervous system functioning, depend on vitamin B12

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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Brown R.C., Lockwood A.H., Sonawane B.R