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Future of Carnitine in the Human Body There is no endogenous catabolism of carnitine in human cells

During autophagy, organelles in the cytoplasm as well as other subunits in the cell are recycled for future remodeling of tissues (121, 376, 408, 409, 428, 441, 442)

A recent study suggested that plasma levels of 5-MT, a compound related to serotonin metabolism, may be decreased in CFS patients, but this has been interpreted as a confounder caused by serotonin-selective reuptake inhibitor (SSRI) use in these patients (40)

Modulation of melatonin secretion by acetyl-L-carnitine in adult and old rats J Pineal Res 1994

Crucially, Crat knockout experiments partially reversed these metabolic improvements, establishing CrAT-mediated SREBP1c inhibition as a key mechanism through which L-carnitine counteracts de novo lipogenesis