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Abstract Mitochondria are the primary intracellular site of oxygen consumption and the major source of reactive oxygen species (ROS), most of them originating from the mitochondrial respiratory chain

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However , scientific proof for this mainly applies to people who already have a deficiency

Elevated MRP1 protein and/or mRNA levels have been confirmed in many hematologic and solid tumors, and in some instances, are predictors of poor response to chemotherapy (4, 811)

Although the exact mechanism of DAQ-induced mitochondrial damage is unknown, it appeared that DAQ preferentially targets specific protein degradation through the binding to thiol groups of proteins