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The expression of inducer 61 (Cyr61), IL-23, and granulocyte-macrophage colony-stimulating factor (GM-CSF) (Ganesan and Rasool, 2019)

Good candidates for peptides for weight loss generally include people who have: A body mass index (BMI) of 30 or higher A BMI of 27 or higher paired with a weight-related health condition, such as high blood pressure, high cholesterol, or diabetes Ongoing struggles with stubborn belly fat or a slow metabolism Age-related fat gain, particularly common among men in their 30s, 40s, 50s, and beyond A weight-loss plateau despite staying consistent with exercise and a clean diet Weight gain linked to a hormonal imbalance or low testosterone Peptide therapy is not appropriate for everyone, however

Ex vivo studies have shown that increasing glucose metabolism with dichloroacetate, a pyruvate mimetic that activates PDH, increases glycolytic flux and improves LV function.87 This has been followed up in vivo , where dichloroacetate administration returned rates of glucose metabolism of diabetic rats to control levels.88 This occurred alongside reversal of impaired diastolic function and normalisation of blood glucose concentrations