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After transfection and growth for 48 h, 10 M DCFH-DA was added into 1 mL medium and incubated at 37 C for 30 min

Bone morphogenetic protein 4 inhibits pulmonary fibrosis by modulating cellular senescence and mitophagy in lung fibroblasts

In addition, injections of adenoviral vectors expressing small interfering (si)RNA targeting NOX2 (AdsiRNA-NOX2) or NOX4 (AdsiRNA-NOX4) mRNAs, used to knock down NOX2 and NOX4 proteins, in the PVN showed that either AdsiRNA-NOX2 or AdsiRNA-NOX4 significantly attenuated the development of Aldo/NaCl-induced hypertension (Xue et al., 2012)