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doi: 10.2147/IJN.S454794, [DOI] [PMC free article] [PubMed] [Google Scholar] 240.Wang B, Zhuang X, Deng Z-B, Jiang H, Mu J, Wang Q, et al

Mitochondrial ROS sources in diabetes As outlined above, the majority of molecular oxygen is processed by mitochondria involving four-electron reduction of dioxygen to water molecules

It is suggested that phosphorylation impacts on the allosteric regulation of MTHFR via altering the equilibrium of active and inactive states of the enzyme, favoring the inactive state which SAM preferentially binds 21

Exogenous antioxidants primarily originate from food and plants, including vitamins, trace elements, carotenoids, and polyphenols, among others

The image underscores the potential of combining NRF2 inhibitors with existing treatments like sorafenib to overcome resistance in HCC