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[192] engineered the FN III 9-10 and FN III 12-14 fragments through genetic manipulation, resulting in the development of a recombinant FN fragment, FN III 9-10/1214 , which was subsequently covalently conjugated to the fibrin scaffold

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However, it would be easier to identify and record the number of hospitalizations, intensive care unit visits, and fatalities during vaccine trials when compared to infections, thus making it more feasible to assess the efficacy of a vaccine against severe disease

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