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Results HCC cells exhibit the activation of VB2 metabolism As the activation levels of metabolic pathways can be quantified by integrating the expression levels of pathway-related genes, we defined a VB2 metabolism gene signature ( SLC52A1 , SLC52A2 , SLC52A3 , RFK , FLAD1 , ACP5 , and ENPP1 ) based on the Reactome pathway database, and then calculated a VB2 metabolism score by integrating the gene signature

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Based on the physiological structure of the retina and the characteristics of blue light induced retinal lesions, mouse retinal photoreceptor cells (661W cells) and human retinal pigment epithelial cells (ARPE-19 cells) are commonly used cell models for light damage (Figure 3)