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DATS inhibited bacterial lipopolysaccharide (LPS)-induced macrophage activation by limiting LPS binding to toll-like receptor 4 (TLR4) and blocking the upregulation of TLR4 and TLR4-associated molecule MyoD88 expression (37)

Glutamate receptor Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells

doi: 10.3389/fnut.2022.856287 3

391 Lactobacillus paracasei R3 and Bacteroides faecis can both restore the integrity of the gut barrier by affecting Th17/Treg homeostasis, which in turn increases the expression of tight junction proteins and regulates the gut microbiota

This helps to attenuate monocrotaline-induced pulmonary artery endothelial dysfunction and PAH in rats (Li et al., 2014