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Description
It is commonly investigated in preclinical research models relating to metabolic signalling pathways, cellular energy regulation, and enzymatic activity associated with nicotinamide N-methyltransferase (NNMT) interaction studies
5-Amino-1MQ is a small molecule membrane-permeable inhibitor of the enzyme Nicotinamide N-methyltransferase (NNMT)
Metabolic Rewiring: By stopping the conversion of nicotinamide (NAM) into 1-methylnicotinamide (1-MNA), the cell is forced to recycle NAM into NAD+
BioMed Research International 2021:9924314
Aging Cell
