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Using metabolite kinetics with the assumption that Cys and Met are the metabolites of GSH, expected concentrations of Cys and Met of above 20 and 50 M were estimated when GSH was administered at 50 mg/kg body weights every 205.4 min for Cys and 427.4 min for Met

To investigate the function of CBS in this process, we silenced its expression by CRISPR/cas9 mediated gene knockout strategy (sg CBS ) in SCD erythroblasts (Fig

Considered alone, these low ALT rises were not diagnostic of hepatitis

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