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K.BenedetJ.et al (2011a)

Potential interactions of vitamin E with drugs Ex vivo inactivation of drugs The first class of nutrientdrug interactions comprises chemical reactions (for example, complexation, hydrolysis, precipitation, oxidation) between a nutrient and a drug, which occur within the galenic formulation and mainly outside of the body ( Reference Chan 24 )

The AGXT enzyme can also convert glyoxylate and alanine to glycine and pyruvate

doi: 10.1016/S0140-6736(06)69525-1

US Food and Drug Administration 3
