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(1997b)

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GST non-enzymatic functions GSTs are also implicated as modulators of signal transduction pathways implicated in cell survival and apoptosis, where they control the activity of members of the mitogen-activated protein kinase (MAPK) family 24,25

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21 Iron deficiency-induced heme reduction directly affects oxygen transport and tissue oxygen utilization

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Overall, adipocytes rich in 6 PUFAs tend to secrete higher TNF-/IL-6 and leptin, whereas 3-rich tissue promotes adiponectin and immune-resolving signals 364,365,366,367

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