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5A-5Bis distance from apex (mm), and the y-axis is percentage loss (%)

Therefore, to understand the effects of amino acid metabolism on macrophage function, it is necessary to analyze the node-specific roles of different amino acids within a unified metabolic network framework

A peer-reviewed study found that GHRP-2 reduced expression of Cd86, Nos2, and tnfa (all with statistical significance at P less than 0.01), suggesting inhibited M1 macrophage polarization

CB-839, a GLS inhibitor that blocks the conversion of glutamine into glutamate, reduced the production of R-2-HG in AML cell lines and patient tissues harboring IDH1/2 mutations 123

The co-administration of drugs reduces mortality but also introduces more drugdrug interactions and increases the risk of developing immune reconstitution inflammatory syndrome (IRIS) [66]