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The ISO/TR 10993-22 document clearly states: The manufacturing and use of nanomaterials are due to their specific properties, which may be related to the reduction in size accompanied by surface roughness. Therefore, the evaluation of nanomaterials cannot rely solely on traditional material testing methods

A substantial increase in the renal malondialdehyde (MDA) level together with a discernible reduction in the reduced-glutathione (GSH) level and the enzyme activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) was observed in birds that fed on an AFT-contaminated diet when compared to other groups

Nevertheless, in vitro models remain a crucial first step toward a deeper understanding of how dAGEs are digested and transformed in the human gastrointestinal tract

Ke T, Tinkov AA, Skalny AV, Santamara A, Rocha JBTda, Bowman AB, Chen W, Aschner M (2023) Epigenetics and methylmercury-induced neurotoxicity, evidence from experimental studies