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Furthermore, other laboratory experiments allow conclusions about other therapeutic effects of the peptide, such as nerve cell regeneration, protective action during drug withdrawal syndrome, and even in the case of seizures occurring with their excessive intake

Anti-inflammatory pathways of -MSH peptides.Endocrine Reviews(2010)

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Dose-response relationships appear to be tissue-specific, with adipose tissue showing high sensitivity while other tissues may require higher concentrations for detectable effects