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For instance, structural changes in the CHCA matrix molecule have a notable influence on the degree of ionization and the detection range of the analytes in MALDI

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The expression of group III mGluRs was detected in several types of cancers, including but not limited to colorectal, laryngeal squamous cell, breast cancers, osteosarcoma, and melanoma ( 4.1.3.1 mGluR4 and glioblastoma Different from the report that the activation of mGluR1 and mGluR5 is associated with an increase in tumor cell proliferation and migration as well as a poor outcome in glioma ( via Gli-1 ( 4.1.3.2 mGluR4 and colorectal cancer Several years ago, the expression of mGluR4 was detected in colon adenocarcinoma ( In vitro , the treatment of different colorectal cancer cell lines (SNU-61, SNU-81, SNU-407, SNU-1033, SNU-1047, SNU-C2A, SNU-C4, and SNU-C5) with the mGluR4 agonist (L-AP 4) increased the proliferation only in SNU-81 cells