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In fact, its the added acetyl group that allows it to cross the blood-brain barrier, which standard L-carnitine doesnt do as easily

The natural history of mediumchain acyl CoA dehydrogenase deficiency in the Netherlands: clinical presentation and outcome

10.1006/jmcc.1999.0968 J

Consistent with this postulate, we observed the greater increase in pSer-IRS-1 in women with stronger severity of depressive symptoms independently of use of psychotropic medications
