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The intermittent treatment design follows preclinical evidence that demonstrated senescent cells require 24 weeks to develop and complete senescent cell clearance is not required for disease modifying effects

Studies show that the increased fat burning associated with fragment 176-191 directly correlates with energy expenditure and thus weight reduction, leading to a nearly 50% reduction in weight gain in obese animals over a three-week course [4]

In children 6 months to less than 12 years of age, DUPIXENT should be given by a caregiver

The Princeton, NJ site is currently enrolling patients for the Chronic Lower Back Pain study