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2.11 LCMS analysis of TVEAE LCMS analysis was performed on a UHPLC Q Exactive Orbitrap mass spectrometry system (ThermoFisher, USA) equipped with a Waters Acquity UHPLC HSS T3 column (2.1 100 mm, 1.8 m)

In addition, Dcr-2 and Ago-2 can have functions that are not directly related to the siRNA pathway of antiviral defense (summarized in Table 2 and further discussed in section 6)

Particular attention to dietary quality is warranted, especially in light of emerging and re-emerging nutritional deficiencies that may compromise immune function and exacerbate disease susceptibility

These include cannabinol (CBN), cannabigerol (CBG), cannabichromene (CBC), and tetrahydrocannabivarin (THCV), among others

In most cases, the entire amount of those antioxidants is greatly reduced (over 95%) within the cytosol, chloroplast, and mitochondria, with oxidized forms accumulating only in compartments with less efficient redox recycling mechanisms, like vacuoles and apoplasts (Noctor et al., 2018)