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Note that P2Y12, P2Y6, and P2X4 inhibition prevents microglia (green) from transforming into jellyfish at the glial limitans

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Increased oxidative stress in hepatitis C may be explained by chronic inflammation, and the continued generation of ROS/ RNS by NADPH oxidase 2 (NOX2) of Kupffer cells and polymorphonuclear cells in the liver [103]