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These large-scale studies would also help establish evidence-based guidelines for EGCG supplementation in clinical practice [125]

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GA is subsequently hydroxylated by CsiD and the product L2HG is oxidised to KG by the dehydrogenase LhgO that couples to the respiratory chain by reducing the quinone pool

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For example, H 2 O 2 reversibly inhibits key PTPs, facilitating the activation of growth-factor kinase cascades such as MAPK and p38 [2, 113]

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